What is the difference between an Abbreviation, an Acronym, and an Initialism? An Abbreviation is a shortened form of a word or phrase (example: Miss is an abbreviation of Mistress). An Acronym is a word formed from the initial letters of the words, (example: Light Amplification by Stimulated Emission of Radiation). An Initialism is an Abbreviation consisting of initial letters pronounced separately (example: BBC is an initialism for the British Broadcasting Corporation). "Get Into Knowledge"